CalciMedica, Inc., a clinical-stage biotechnology company, focuses on developing therapies for life-threatening inflammatory diseases with unmet needs. Its proprietary technology targets the inhibition of calcium release-activated (CRAC) channels designs to modulate the immune response and protect against tissue cell injury in life-threatening inflammatory diseases. Its lead product candidate is Auxora, a proprietary intravenous-formulated CRAC channel inhibitor for the treatment of acute pancreatitis, asparaginase-associated acute pancreatitis, and acute kidney injury. The company is based in La Jolla, California.
CalciMedica Reports Second Quarter 2026 Financial Results and Provides Clinical & Corporate Updates
CalciMedica reported financial results for Q2 2026, highlighting a recently closed private placement of up to $49 million in gross proceeds, including $15 million upfront, which extends the cash runway into the second half of 2027.
The company received FDA alignment on the primary endpoint for its Phase 2b acute pancreatitis trial, focusing on reducing new-onset severe respiratory failure, with data for the Auxora PAH Phase 1b trial and CM5480 IND submission expected in mid-2027.
Q2 net loss was $7.7 million, or $0.45 per share, compared to a net loss of $6.0 million in the prior year, while R&D and G&A expenses both decreased year-over-year due to reduced clinical and consulting activities.