Immuneering Corporation is a biopharmaceutical company dedicated to developing novel therapeutic candidates in the fields of oncology (cancer) and neuroscience. Leading its clinical development efforts are two key drug candidates: IMM-1-104, a dual-MEK inhibitor intended for the treatment of various cancers, including pancreatic, melanoma, colorectal, and non-small cell lung cancer, specifically those driven by RAS and/or RAF gene mutations. The second is IMM-6-415, which is being developed to treat solid tumors. Beyond these advanced-stage programs, Immuneering's early-stage pipeline includes five oncology initiatives aimed at components of the MAPK or mTOR signaling pathways, along with two neuroscience programs, all currently in the discovery phase. Founded in 2008, Immuneering Corporation is headquartered in Cambridge, Massachusetts. It was formerly a subsidiary of Teva Pharmaceutical Industries Limited.
Immuneering to Present at the 41st Annual Meeting of the Society for Immunotherapy of Cancer (SITC)
Immuneering will present a poster at the 41st Annual SITC meeting (November 4-8, 2026, Phoenix) showing that atebimetinib enhances PD-1 checkpoint blockade in RAS mutant preclinical tumor models.
The findings provide mechanistic support for a planned Phase 2 study of atebimetinib combined with PD-1 blockade in lung cancer patients.
Atebimetinib is Immuneering's lead oral, once-daily MEK inhibitor; the company is also running the pivotal MAPKeeper 301 trial in first-line pancreatic cancer.