MAIA Biotechnology, Inc. is a clinical-stage biotech firm dedicated to discovering, developing, and commercializing treatments for various cancers, with a primary focus on non-small cell lung cancer. The company's leading experimental compound, THIO, is an investigational drug candidate that utilizes a unique dual mechanism by targeting telomeres and stimulating an immune response. Established in 2018, the enterprise maintains its headquarters in Chicago, Illinois.
MAIA Biotechnology Reports Strong Initial Efficacy Data in Third-Line Non-Small Cell Lung Cancer from Phase 2 THIO-101 Part C Expansion Trial
MAIA Biotechnology reported positive interim efficacy data from the Part C expansion of its Phase 2 THIO-101 trial evaluating ateganosine in third-line NSCLC. The data showed a disease control rate of 90.5% in the evaluable population, significantly outperforming the approximate 25-35% rate associated with current chemotherapy treatments.
These results align with previously reported signals from earlier trial parts, maintaining high efficacy despite a more heavily pre-treated patient population in this cohort.
The company noted that treatment with ateganosine followed by cemiplimab has demonstrated an acceptable safety profile to date.