MAIA Biotechnology, Inc. is a clinical-stage biotech firm dedicated to discovering, developing, and commercializing treatments for various cancers, with a primary focus on non-small cell lung cancer. The company's leading experimental compound, THIO, is an investigational drug candidate that utilizes a unique dual mechanism by targeting telomeres and stimulating an immune response. Established in 2018, the enterprise maintains its headquarters in Chicago, Illinois.
MAIA Biotechnology Achieves Patient Enrollment Milestones in Ongoing Phase 2 and Pivotal Phase 3 Clinical Trials in Non-Small Cell Lung Cancer
MAIA Biotechnology reached enrollment milestones across its ateganosine NSCLC trials, with 150 patients treated and Part C of the Phase 2 THIO-101 trial fully enrolled.
The pivotal Phase 3 THIO-104 trial has 65 patients enrolled, tracking toward its target of 100 by year-end 2026 with an interim analysis planned in 2027.
The Phase 2 combination with cemiplimab showed a 90.5% interim disease control rate, close to triple standard-of-care chemotherapy outcomes; ateganosine holds FDA Fast Track designation.