Metagenomi, Inc., a gene editing biotechnology company, develops therapeutics for patients using metagenomics-derived genome editing toolbox in the United States. The company's genome editing toolbox includes programmable nucleases, base editors, and RNA and DNA-mediated integration systems, such as prime editing systems and clustered regularly interspaced short palindromic repeat-associated transposases. It has a strategic collaboration and license agreement with ModernaTX, Inc. focusing on new genome editing system for in vivo human therapeutic applications; a development, option, and license agreement with Affini-T Therapeutics, Inc. to develop and commercialize gene edited T-cell receptor-based therapeutic products in the field of treatment, prevention, or diagnosis of human cancer; and a collaboration and license agreement with Ionis Pharmaceuticals, Inc. to research, develop, and commercialize investigational medicines using genome editing technologies. The company was incorporated in 2016 and is based in Emeryville, California.
Metagenomi Therapeutics Reports Business Updates and Second Quarter 2026 Financial Results
Metagenomi reported second quarter financial results, ending the period with $120.7 million in cash and marketable securities, which the company anticipates will fund operations into the fourth quarter of 2027.
The company confirmed it remains on track to submit an IND application for its lead hemophilia A program, MGX-001, in the fourth quarter of 2026, with IND-enabling studies expected to wrap up by the end of the third quarter.
R&D expenses were flat year-over-year at approximately $22.5 million, while G&A expenses decreased to $6.0 million from $7.0 million in the prior-year period.