Tenaya Therapeutics, Inc., a clinical-stage biotechnology company, discovers, develops, and delivers therapies for heart disease in the United States. Its lead product candidate includes TN-201, a gene therapy for myosin binding protein C3-associated hypertrophic cardiomyopathy that is in Phase 1b/2 clinical trial; TN-401, a gene therapy for plakophilin 2-associated arrhythmogenic right ventricular cardiomyopathy, which is in Phase 1b/2 clinical trial; and TN-301, a small molecule histone deacetylase-6 for heart failure with preserved ejection fraction that is in phase 1 clinical trial. The company develops its products through gene addition, gene editing, gene silencing, and cellular regeneration. It has a research collaboration agreement with Alnylam Pharmaceuticals, Inc. to identify and validate novel gene targets for the potential treatment of cardiovascular disease. Tenaya Therapeutics, Inc. was incorporated in 2016 and is headquartered in South San Francisco, California.
Tenaya Therapeutics Reports Second Quarter 2026 Financial Results and Provides Business Update
Tenaya Therapeutics reported Q2 2026 net loss of $43.4 million, or $0.20 per share, driven by a $21.8 million non-cash impairment charge related to the early termination of its manufacturing facility lease.
The company ended the quarter with $78.1 million in cash, which it expects to fund operations into Q3 2027, supported by a $10 million upfront payment from a collaboration with Alnylam.
Positive interim data were reported from the MyPEAK-1 and RIDGE-1 trials for TN-201 and TN-401, with additional data and regulatory updates expected in Q4 2026.
Eric Hyllengren was appointed Chief Financial Officer, effective July 13, 2026.