ZyVersa Therapeutics, Inc. is a biopharmaceutical firm in its clinical development phase, dedicated to advancing and commercializing therapies for renal (kidney) and inflammatory disorders. The company's pipeline prominently features VAR 200, a cholesterol efflux modulator aimed at addressing kidney diseases such as focal segmental glomerulosclerosis, Alport syndrome, and diabetic kidney disease. Furthermore, ZyVersa is advancing IC 100, a pioneering inflammasome ASC inhibitor positioned to tackle a wide array of inflammatory conditions. The company maintains its corporate headquarters in Weston, Florida.
ZyVersa Therapeutics Reports First Quarter 2026 Financial Results and Provides Business Update
ZyVersa reported a Q1 2026 net loss of $1.8 million, an improvement from $2.3 million in the prior year, driven by a 78% drop in R&D spending due to a paused study and executive retirement.
The company ended the quarter with $0.3 million in cash, stating it is only sufficient to fund operations on a month-to-month basis and requires immediate additional financing.
Management plans to file an IND for IC 100 in Q4 2026 and initiate a Phase 2a trial for VAR 200 in H2 2026, contingent on securing capital.